Tenofovir CAS 147127-20-6 Assay 98.0%~102.0% API Anti-HIV Factory

Short Description:

Name: Tenofovir 

CAS: 147127-20-6

Appearance: White or Off-White Crystalline Powder

Assay: 98.0%~102.0% (on anhydrous basis) 

Tenofovir is used for the treatment of Chronic Heptatitis B as well as prevention and treatment of HIV/AIDS.

High Quality, Commercial Production 

Inquiry: alvin@ruifuchem.com


Product Detail

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Description:

Chemical Properties:

Name Tenofovir
Synonyms (R)-PMPA; (R)-9-(2-Phosphonomethoxypropyl)Adenine
CAS Number 147127-20-6
CAT Number RF-API07
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C9H14N5O4P
Molecular Weight 287.22
Melting Point  276.0-280.0℃
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White or Almost White Crystalline Powder 
Assay / Analysis Method 98.0%~102.0% (on anhydrous basis)
Solubility Slightly Soluble in Water (0.1g in 100ml); Practically Insoluble in Methanol(0.01g in 100ml and over)
Identification UV Absorbance at about 261nm  
Identification HPLC The retention time of the principal peak in the test sample should match with that of the standard 
Sulphate Ash ≤1.5%
Water (K.F) ≤3.0%
Specific Optical Rotation -19.0° ~ -23.0° (at 25℃ anhydrous basis)
PMPA Monoester Impurity ≤1.5% (HPLC)
Any Single Max Impurity ≤0.5% (HPLC)
Total Impurities ≤3.0% (HPLC)
Enantiomeric Purity ≤0.5% (HPLC)
9-Propenyl Adenine  ≤75ppm (HPLC) 
Test Standard Enterprise Standard

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture.

Advantages:

1

FAQ:

Application:

Tenofovir (CAS: 147127-20-6) is an acyclic phosphonate nucleotide analogue and reverse-transcriptase inhibitor (NtRTI). It is used as an anti-HIV agent. Antiviral. Tenofovir disoproxil (Viread) is the first nucleotide analogue approved by the American FDA to treat HIV-1 infections. Tenofovir is a drug used for the treatment of chronic heptatitis B as well as prevention and treatment of HIV/AIDS. It inhibits the activity of HIV reverse transcriptase through competing with the natural substrate deoxyadenosine 5’-triphosphate, causing the termination of DNA chain.

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